From the Novell website regarding BlackBerry Enterprise Server and GroupWise...

Please note the following information from Research In Motion regarding BES support for GroupWise users. Customers still using BES 4.x should make plans to upgrade to BES 5.x as soon as possible.

  • BES 4.1.7 developer support ends on October 15, 2011.
  • BES 4.1.7 and BES 5.x have been certified with GroupWise 8.02 HP3.
  • BES 5.x will support GroupWise 2012 in early 2012.
  • Before updating to GroupWise 2012, customers using BES 4.x should upgrade to BES 5.x.

Additional details are available at Research In Motion's lifecycle web page.